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Text Box: Publications of Polgenix, Inc. (former Novasite)
Salom D, Cao P, Yuan Y, Miyagi M, Feng Z, Palczewski K. “Isotopic labeling of mammalian G protein-coupled receptors heterologously expressed in Caenorhabditis elegans.” Anal Biochem. 2015 Mar 1;472:30-6. 
Padayatti PS, Wang L, Gupta S, Orban T, Sun W, Salom D, Jordan SR, Palczewski K, Chance MR. “A hybrid structural approach to analyze ligand binding by the serotonin type 4 receptor (5-HT4).” Mol Cell Proteomics. 2013 May;12(5):1259-71. 
Salom D, Padayatti PS, Palczewski K.  “Crystallization of G protein-coupled receptors.” Methods Cell Biol. 2013;117:451-68. 
Jastrzebska B, Salom D, Jin H, Cao P, Sun W, Palczewski K, Feng Z.  “Expression of mammalian G protein-coupled receptors in Caenorhabditis elegans.” Methods Enzymol. 2013;520:239-56. 
Salom D, Cao P, Sun W, Kramp K, Jastrzebska B, Jin H, Feng Z, Palczewski K.  “Heterologous expression of functional G-protein-coupled receptors in Caenorhabditis elegans.” FASEB J. 2012 Feb;26(2):492-502. 
Cao P, Sun W, Kramp K, Zheng M, Salom D, Jastrzebska B, Jin H, Palczewski K, Feng Z.  “Light-sensitive coupling of rhodopsin and melanopsin to G(i/o) and G(q) signal transduction in Caenorhabditis elegans.” FASEB J. 2012 Feb;26(2):480-91. 
Salom D, Wang B, Dong Z, Sun W, Padayatti P, Jordan S, Salon JA, Palczewski K.  “Post-translational modifications of the serotonin type 4 receptor heterologously expressed in mouse rod cells.” Biochemistry. 2012 Jan 10;51(1):214-24. 
 “Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes”; Palczewska G, Maeda T, Imanishi Y, Sun W, Chen Y, Williams DR, Piston DW, Maeda A, Palczewski K.; Nat Med. 2010 Dec;16(12):1444-9.
”Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy”; Hunter JJ, Masella B, Dubra A, Sharma R, Yin L, Merigan WH, Palczewska G, Palczewski K, Williams DR.; Biomed Opt Express. 2010 Dec 17;2(1):139-48.
“Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues”; Orban T, Palczewska G, Palczewski K.; J Biol Chem. 2011 May 13;286(19):17248-58.
“Primary amines protect against retinal degeneration in mouse models of retinopathies”; Maeda A, Golczak M, Chen Y, Okano K, Kohno H, Shiose S, Ishikawa K, Harte W, Palczewska G, Maeda T, Palczewski K.; Nat Chem Biol. 2012 Dec 25;8(2):170-8.
“Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage”; Okano K, Maeda A, Chen Y, Chauhan V, Tang J, Palczewska G, Sakai T, Tsuneoka H, Palczewski K, Maeda T.; J Neurochem. 2012 Apr;121(1):146-566. 
“Imaging of protein crystals with two-photon microscopy”; Padayatti P, Palczewska G, Sun W, Palczewski K, Salom D.; Biochemistry. 2012 Feb 28;51(8):1625-37.
 “QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles”; Maeda T, Dong Z, Jin H, Sawada O, Gao S, Utkhede D, Monk W, Palczewska G, Palczewski K.; Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):455-66.
“In vivo two-photon imaging of the mouse retina”; Sharma R, Yin L, Geng Y, Merigan WH, Palczewska G, Palczewski K, Williams DR, Hunter JJ.; Biomed Opt Express. 2013 Jul 9;4(8):1285-93.
“Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo”; Maeda T, Lee MJ, Palczewska G, Marsili S, Tesar PJ, Palczewski K, Takahashi M, Maeda A.; J Biol Chem. 2013 Nov 29;288(48):34484-93.
“Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration”; Chen Y, Palczewska G, Mustafi D, Golczak M, Dong Z, Sawada O, Maeda T, Maeda A, Palczewski K.; J Clin Invest. 2013 Dec;123(12):5119-34.
“Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice”; Maeda A, Palczewska G, Golczak M, Kohno H, Dong Z, Maeda T, Palczewski K.; Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1428-37.
 “Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye”; Palczewska G, Dong Z, Golczak M, Hunter JJ, Williams DR, Alexander NS, Palczewski K.; Nat Med. 2014 Jul;20(7):785-9.
“Endogenous fluorophores enable two-photon imaging of the primate eye”; Palczewska G, Golczak M, Williams DR, Hunter JJ, Palczewski K.; Invest Ophthalmol Vis Sci. 2014 Jun 26;55(7):4438-47.
“Human infrared vision is triggered by two-photon chromophore isomerization”; Palczewska G, Vinberg F, Stremplewski P, Bircher MP, Salom D, Komar K, Zhang J, Cascella M, Wojtkowski M, Kefalov VJ, Palczewski K.; Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5445-54.
“Imaging of rhodopsin crystals with two-photon microscopy”. Palczewska G, Salom D.; Methods Mol Biol. 2015;1271:55-64. 
“Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations”; Zhang N, Tsybovsky Y, Kolesnikov AV, Rozanowska M, Swider M, Schwartz SB, Stone EM, Palczewska G, Maeda A, Kefalov VJ, Jacobson SG, Cideciyan AV, Palczewski K.; Hum Mol Genet. 2015 Jun 1;24(11):3220-37.
“Molecular pharmacodynamics of emixustat in protection against retinal degeneration”; Zhang J, Kiser PD, Badiee M, Palczewska G, Dong Z, Golczak M, Tochtrop GP, Palczewski K.; J Clin Invest. 2015 Jul 1;125(7):2781-94.
“Semi-automated discrimination of retinal pigmented epithelial cells in two-photon fluorescence images of mouse retinas”; Alexander NS, Palczewska G, Palczewski K.; Biomed Opt Express. 2015 Jul 23;6(8):3032-52.
 “Periscope for noninvasive two-photon imaging of murine retina in vivo”; Stremplewski P, Komar K, Palczewski K, Wojtkowski M, Palczewska G.; Biomed Opt Express. 2015 Aug 13;6(9):3352-61.
 “Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye”; Living Primate Eye. Sharma R, Williams DR, Palczewska G, Palczewski K, Hunter JJ.; Invest Ophthalmol Vis Sci. 2016 Feb;57(2):632-46.
“In Vivo Two-Photon Fluorescence Kinetics of Primate Rods and Cones”; Sharma R, Schwarz C, Williams DR, Palczewska G, Palczewski K, Hunter JJ.; Invest Ophthalmol Vis Sci. 2016 Feb;57(2):647-57.
“Image registration and averaging of low laser power two-photon fluorescence images of mouse retina”; Alexander NS, Palczewska G, Stremplewski P, Wojtkowski M, Kern TS, Palczewski K.; Biomed Opt Express. 2016 Jun 20;7(7):2671-91.
 “Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration”; Chen Y, Palczewska G, Masuho I, Gao S, Jin H, Dong Z, Gieser L, Brooks MJ, Kiser PD, Kern TS, Martemyanov KA, Swaroop A, Palczewski K.; Sci Signal. 2016 Jul 26;9(438).
“Safety assessment in macaques of light exposures for functional two-photon ophthalmoscopy in humans”; Schwarz C, Sharma R, Fischer WS, Chung M, Palczewska G, Palczewski K, Williams DR, Hunter JJ.; Biomed Opt Express. 2016 Nov 16;7(12):5148-5169.
“Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium”; Palczewska G, Maeda A, Golczak M, Arai E, Dong Z, Perusek L, Kevany B, Palczewski K.; J Biol Chem. 2016 Dec 23;291(52):26937-26949.
Palczewska G, Maeda T, Imanishi Y, Sun W, Chen Y, Williams DR, Piston DW, Maeda A, Palczewski K. “Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes” Nature Medicine published online 14 November 2010
Salom D*, Wu N*, Sun W*, Dong Z, Palczewski K, Jordan S, Salon JA. “Heterologous expression and purification of the serotonin type 4 receptor from transgenic mouse retina” Biochemistry 4750,13296-307 (2008) (* indicates co-first author)
Li N, Salom D, Zhang L, Harris T, Ballesteros J, Golczak M, Jastrzebska B; Palczewski K, Kurahra C, Juan T, Jordan S, Salon J. Heterologous Expression of the Adenosine A1 Receptor in Transgenic Mouse Retina". Biochemistry 46, 8350-8359 (2007).
Lodowski DT, Salom D, Le Trong I, Teller DC, Ballesteros JA, Palczewski K, Stenkamp RE. "Crystal packing analysis of rhodopsin crystals". J. Struct. Biol. 158, 455-62 (2007)
Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, Palczewski K. "Crystal structure of a photoactivated deprotonated intermediate of rhodopsin". Proc. Natl. Acad. Sci. USA. 103, 16123-8 (2006).
Salom D, Le Trong I, Pohl E, Ballesteros JA, Stenkamp RE, Palczewski K, Lodowski DT. "Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals". J. Struct. Biol. 156, 497-504 (2006).
Zhang L, Salom D, He J, Okun A, Ballesteros J, Palczewski K, Li N. "Expression of functional G protein-coupled receptors in photoreceptors of transgenic Xenopus laevis". Biochemistry. 44, 14509-18 (2005).
Salom D, Li N, Zhu L, Sokal I, & Palczewski K. “Purification of the G protein-coupled receptor rhodopsin for structural studies" in G protein-coupled receptor-protein interactions (eds. George S.R ., & O'Dowd B.F.) (2005).
Ballesteros J, Palczewski K. "G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin". Curr. Opin. Drug Discov. Devel. 4, 561-74 (2001).